pentobarbital will reduce the level or impact of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
Drugs which have step therapy associated with Every single prescription. This restriction typically demands that particular criteria be met prior to acceptance with the prescription.
Check Closely (1)pentobarbital will minimize the level or influence of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Caution when discontinuing CYP3A4 inducers which have been coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may possibly improve and may result in possibly deadly respiratory despair.
pentobarbital will lessen the level or outcome of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Strong CYP3A4 inducers are envisioned to bring about significant decreases in sildenafil plasma stages
Check Carefully (1)pentobarbital will reduce the level or effect of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Minor (one)pentobarbital will reduce the level or influence of paclitaxel protein certain by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.
After stopping a CYP3A4 inducer, because the effects from the inducer decline, the fentanyl plasma concentration will increase which could increase or lengthen both the therapeutic and adverse effects.
pentobarbital will lower the extent or outcome of etravirine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or impact of ritonavir by affecting hepatic/intestinal enzyme read more CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Sturdy or reasonable CYP3A4 inducers could improve rate of diazepam elimination; hence, efficacy of diazepam can be lowered.
pentobarbital will lessen the extent or influence of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
pentobarbital will decrease the extent or outcome of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of CYP3A4 inducers might lower sufentanil concentrations and efficacy, maybe precipitating withdrawal syndrome in patients that have formulated Actual physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers could enhance sufentanil plasma focus.
pentobarbital will minimize the extent or outcome of zaleplon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.